As you are aware, the Marketing Research Bureau has conducted a survey of the Plasma Fractions Market in the United States every year since 1974. We intend to conduct this study again this year. The 2008 Plasma Fractions Market in the United States report provides estimated sales in units and dollars of all the therapeutic plasma protein products by major competitor, as well as of recombinant clotting factors. It also analyzes the recent developments on plasma supply and fractionation, product distribution, and introduction of new therapeutic plasma proteins. As in previous years, the major fractionators are profiled. The table of contents of the report is enclosed for your information. For customers who only need selected sections of the report, individual chapters may be purchased separately. Please call for pricing information. Sincerely, Patrick L. Robert President Table of Contents July 2008     Page EXECUTIVE SUMMARY 1 1) PLASMA COLLECTIONS 15 1.1) Consolidation of the Plasma Collection Sector 16 1.2) Plasma Quality Enhancement 25 1.3) Major Plasma Collection Organizations 27 2) PLASMA FRACTIONATION 46 2.1) Processing Capacity and Throughput 46 2.2) Production Yields 48 3) MARKET OVERVIEW 61 3.1) The Plasma Fractions Market by Product 61 3.2) Pricing Trends For Finished Plasma Products 65 3.3) The Plasma Fractions Market by Product 65 3.4) The Plasma Fractions Market by Company 66 3.5) Historical Development 69 3.6) Recent Products Approvals 71 4) IMMUNE GLOBULIN MARKET 74 4.1) Intramuscular Polyvalent Immune Globulin Market and Hyperimmune Globulin 74 4.2) Polyvalent Intravenous Immune Globulin (IVIG) Market 85 5) ALBUMIN MARKET 105 6) HEMOPHILIA CARE MARKET 113 6.1) Introduction 113 6.2) Historical Development 113 6.3) Hemophilia Patient Population 114 6.4) Hemophilia Treatment Centers and Home Care 115 6.5) Historical Development 116 6.6) Factor VIII Market 120 6.7) Factor IX Market 134 6.8) Von Willebrand Disease Market 135 6.9) Inhibitor Market 145 6.10) Other Bleeding Disorders 153 7) ALPHA-1 ANTITRYPSIN MARKET 153 8) ANTITHROMBIN III MARKET 159 9) FIBRIN SEALANT MARKET 159 10) OTHER PLASMA PRODUCTS 162 11) DISTRIBUTION OF PLASMA PRODUCTS 165 12) PROFILES OF THE MAJOR FRACTIONATORS 177 12.1) Baxter Bioscience 177 12.2) Bayer Healthcare 184 12.3) Biotest Biopharmaceuticals 186 12.4) CSL Behring 187 12.5) Grifols USA 193 12.6) Octapharma USA 197 12.7) Omrix Biopharmaceuticals 198 12.8) Ortho Clinical Diagnostics 199 12.9) Talecris Biotherapeutics 200 List of Tables and Charts   Page Plasma Fractions Market by Major Company from 1992 to 2008 - without recombinant Factors ($ Million) Plasma Fractions Market by Company - with/without Recombinant Products Plasma Fractions Market by Product - 2008 - with Recombinant Factors - without Recombinant XI 12 13 14   PLASMA COLLECTIONS & FRACTIONATION Plasma Collections by Organization Plasma Processed by the Fractionators 2002 to 2008 Plasma Collected and Exported – 1996 to 2008 Plasma Collections in the U.S. – 1996- to 2010 (chart) Number of licensed Plasma Centers in the U.S. 1996-2010 (chart) Export of Plasma from 1990 to 2008 (liters & Dollars) Export of Plasma by Country of Destination in 2008 Export of Plasma from 1992 to 2008 in liters (Chart) Price of Plasma exported from the U.S. - 1992 to 2008 (Chart) Price of Source and Recovered Plasma in the U.S. 1986 to 2008 Price of Source and Recovered Plasma in the U.S. (Chart) Estimated Plant Capacity & Throughput in 2008 19 20 21 22 23 37 38 39 40 44 45 46   PLASMA FRACTIONS Plasma Fractions Market by Product from 1986 to 2008 ($MM) 51 U.S. Plasma Fractions Market by Company ($MM) in 2008 52 Market Shares by Company with Recombinant Products (Chart) 53 Market Shares by Company without Recombinant Products (Chart) 54 Product Mix by Major Company with Recombinant Products 55 Product Mix by Major Company without Recombinant Products 56 Product Mix without Recombinant Products (Chart) 57 Product Mix with Recombinant Products (Chart) 58 Market History 1991 – 2008 with/without Rec. Products (Chart) 59 Market Shares by Company1996 – 2008 without Rec. Prod. (Chart) 60 51 52 53 54 55 56 57 58 59 60   IMMUNE GLOBULIN MARKET Polyvalent Intramuscular, Rho(D), Tetanus and Hepatitis B 77 Rabies, Other Immune Globulins and Summary – 2008 78 77 78   INTRAVENOUS IMMUNE GLOBULIN MARKET Polyvalent IGIV Market in the U.S. in 2008 Sales History by Company ($MM) IVIG Sales 1991 - 2008 in Units (Chart) IVIG Sales 1991 – 2008 in Dollars (Chart) Market Shares by Company 1996 - 2008 (Chart) Average Selling Price of IGIV 80 81 82 83 84 88   ALBUMIN & PLASMA PROTEIN FRACTION (PPF) MARKET Albumin Market in Dollars, Units & Market Shares - 2008 Albumin Sales by Company, 1986 - 2008 in Dollars Albumin Sales 1991 - 2008 in Units (12.5 grams) (Chart) Albumin Sales 1991 – 2008 in Dollars (Chart) Sales History 1996 – 2008 (Market Shares by Company) (Chart) 100 101 102 103 104   FACTOR VIII MARKET Factor VIII Market in Dollars, Units & Market Shares in 2008 Total Factor VIII and Von Willebrand ($MM) Factor VIII Market by Company from 1997 to 2008 ($MM) Factor VIII Market by Company from 1997 to 2008 (Units MM) Factor VIII Market Conversion from 1996 to 2008 Factor VIII Sales 1992 – 2008 in Dollars, Recomb./Plasma (Chart) Factor VIII Sales 1987 - 2008 in Units, Recomb./Plasma (Chart) Market Shares by Company 1999 to 2008 (Chart) Factor VIII & von Willebrand Disease Mkt. Shares - 2008 (Chart) Prices of Factor VIII Concentrate 1980 - 2008 124 125 126 127 128 129 130 131 132 133   FACTOR IX MARKET Sales in Dollars, Units & Market Shares – 2008 Factor IX Market by Company, 1996 – 2008 ($MM) Factor IX Market in International Units from 1986 to 2008 Factor IX Unit Sales, 1986 - 2008 (Plasma-derived only) Factor IX Average selling price, 1986 - 2008 (Plasma-derived only) Market Shares by Company (Chart) Market Shares by Company from 1986 to 2008 (Chart) 137 138 139 140 141 142 143   VON WILLEBRAND MARKET Von Willebrand Market in Dollars, Units & Mkt. Shares - 2007 144   INHIBITOR CARE MARKET Factors VIII and IX Concentrate’s Use in Immune Tolerance Inhibitor Care Market by Product & Therapy from 2003 to 2008 Inhibitor Care Market by Product - 2008 150 151 152   OTHER PLASMA PRODUCTS MARKET Alpha-I Antitrypsin Market from 1996 to 2008 ($MM) Antithrombin Market from 2001 to 2008 ($MM) Alpha-I Antitrypsin, Antithrombin, Fibrin Sealant and Thrombin Markets in Dollars, Units & Market Shares 157 158 164     [ Home ] [ MRB ] [ IBPN ] [ Subscription ] [ List of Reports ] [ Production Schedule ] [ US Report ] [ Client List ] [ Data Sample ] [ Directory ][ Worldwide Report ]